Brain - Blog Posts

Surface display of the various structures that play a role in either coloring (e.g. valence circuits) or encoding (interoceptive and cognitive circuits) emotional awareness states source

Birthday presents ✨️

Doodles while listening to this video on the brain and quantum physics

"So you navigate your life with the help of others who held mirrors up for you. People praised your good qualities and criticised your bad habits, and these perspectives -often surprising to you - helped you to guide your life. " - David Eagleman

Meal

fast random shitty doodle I did last year

we’re almost in february and i didn’t post a shit ☠️

Does it bother anyone else that there are parts of your life you don’t remember? You have done and said things that you don’t even know about anymore. That means you don’t even have the right perception of yourself because you don’t even fully know who you are. However, something that you’ve forgotten about could be a prominent memory in somebody else’s mind. It trips me out.

Rock Bottom Gallery [fig.1d]

🍰 Anyone want a slice? 🍰 I think this one took the longest so far😅 so many cookies! So many WRINKLES!! But you know, the wrinklier your brain is, the smarter you are. Plus, you are what you eat… You don’t want to have smooth brain do you? 👁️👄👁️

The link between drawing and seeing in the brain

Drawing an object and naming it engages the brain in similar ways, according to research recently published in JNeurosci. The finding demonstrates the importance of the visual processing system for producing drawings of an object.

(Image caption: Brain activation patterns during object recognition and production. Credit: Fan et al., JNeurosci 2019)

In a study by Fan et al., healthy adults performed two tasks while the researchers recorded brain activity using functional magnetic resonance imaging: they identified pieces of furniture in pictures and produced drawings of those pieces of furniture. The researchers used machine learning to discover similar patterns of brain activity across both tasks within the occipital cortex, an area of the brain important for visual processing. This means people recruit the same neural representation of an object whether they are drawing it or seeing it.

As the participants drew each object multiple times, the activity patterns in occipital cortex remained unchanged, but the connection between occipital cortex and parietal cortex, an area involved in motor planning, grew more distinct. This suggests that drawing practice enhances how the brain shares information about an object between different regions over time.

No context but I came across this image while doing homework

8/1/18 - 2/100 days of productivity

Sorry this is late - I had no WiFi yesterday at all! However, in my only free I made these notes on the brain :)

I hope you’re having a great week!

Don't be afraid to be open minded ; your brain is not going to fall out✌

I hope you like it, a little drawing of Pinky and the brain 😄

I love those two so much 😆✨

“A thought is a Parasite”

~

AKA: When you have an idea & you can’t sleep over it & it wants to manifest out into written form -

it’s using you as it’s host body.

~

do not drink

Aphasia: The disorder that makes you lose your words

It’s hard to imagine being unable to turn thoughts into words. But, if the delicate web of language networks in your brain became disrupted by stroke, illness or trauma, you could find yourself truly at a loss for words. This disorder, called “aphasia,” can impair all aspects of communication. Approximately 1 million people in the U.S. alone suffer from aphasia, with an estimated 80,000 new cases per year.  About one-third of stroke survivors suffer from aphasia, making it more prevalent than Parkinson’s disease or multiple sclerosis, yet less widely known.

There are several types of aphasia, grouped into two categories: fluent (or “receptive”) aphasia and non-fluent (or “expressive”) aphasia. 

People with fluent aphasia may have normal vocal inflection, but use words that lack meaning. They have difficulty comprehending the speech of others and are frequently unable to recognize their own speech errors. 

People with non-fluent aphasia, on the other hand, may have good comprehension, but will experience long hesitations between words and make grammatical errors. We all have that “tip-of-the-tongue” feeling from time to time when we can’t think of a word. But having aphasia can make it hard to name simple everyday objects.  Even reading and writing can be difficult and frustrating.

It’s important to remember that aphasia does not signify a loss in intelligence. People who have aphasia know what they want to say, but can’t always get their words to come out correctly. They may unintentionally use substitutions, called “paraphasias” – switching related words, like saying dog for cat, or words that sound similar, such as house for horse. Sometimes their words may even be unrecognizable.  

So, how does this language-loss happen? The human brain has two hemispheres. In most people, the left hemisphere governs language.  We know this because in 1861, the physician Paul Broca studied a patient who lost the ability to use all but a single word: “tan.” During a postmortem study of that patient’s brain, Broca discovered a large lesion in the left hemisphere, now known as “Broca’s area.” Scientists today believe that Broca’s area is responsible in part for naming objects and coordinating the muscles involved in speech. Behind Broca’s area is Wernicke’s area, near the auditory cortex. That’s where the brain attaches meaning to speech sounds. Damage to Wernicke’s area impairs the brain’s ability to comprehend language. Aphasia is caused by injury to one or both of these specialized language areas.

Fortunately, there are other areas of the brain which support these language centers and can assist with communication.  Even brain areas that control movement are connected to language. Our other hemisphere contributes to language too, enhancing the rhythm and intonation of our speech. These non-language areas sometimes assist people with aphasia when communication is difficult.

However, when aphasia is acquired from a stroke or brain trauma, language improvement may be achieved through speech therapy.  Our brain’s ability to repair itself, known as “brain plasticity,” permits areas surrounding a brain lesion to take over some functions during the recovery process. Scientists have been conducting experiments using new forms of technology, which they believe may encourage brain plasticity in people with aphasia.  

Meanwhile, many people with aphasia remain isolated, afraid that others won’t understand them or give them extra time to speak. By offering them the time and flexibility to communicate in whatever way they can, you can help open the door to language again, moving beyond the limitations of aphasia.

Neuro chip records brain cell activity at higher resolution

Brain functions are controlled by millions of brain cells. However, in order to understand how the brain controls functions, such as simple reflexes or learning and memory, we must be able to record the activity of large networks and groups of neurons. Conventional methods have allowed scientists to record the activity of neurons for minutes, but a new technology, developed by University of Calgary researchers, known as a bionic hybrid neuro chip, is able to record activity in animal brain cells for weeks at a much higher resolution. The technological advancement was published in the journal Scientific Reports.

“These chips are 15 times more sensitive than conventional neuro chips,” says Naweed Syed, PhD, scientific director of the University of Calgary, Cumming School of Medicine’s Alberta Children’s Hospital Research Institute, member of the Hotchkiss Brain Institute and senior author on the study. “This allows brain cell signals to be amplified more easily and to see real time recordings of brain cell activity at a resolution that has never been achieved before.”

The development of this technology will allow researchers to investigate and understand in greater depth, in animal models, the origins of neurological diseases and conditions such as epilepsy, as well as other cognitive functions such as learning and memory.

“Recording this activity over a long period of time allows you to see changes that occur over time, in the activity itself,” says Pierre Wijdenes, a PhD student in the Biomedical Engineering Graduate Program and the study’s first author. “This helps to understand why certain neurons form connections with each other and why others won’t.”

The cross-faculty team created the chip to mimic the natural biological contact between brain cells, essentially tricking the brain cells into believing that they are connecting with other brain cells. As a result, the cells immediately connect with the chip, thereby allowing researchers to view and record the two-way communication that would go on between two normal functioning brain cells.

“We simulated what Mother Nature does in nature and provided brain cells with an environment where they feel as if they are at home,” says Syed. “This has allowed us to increase the sensitivity of our readings and help neurons build a long-term relationship with our electronic chip.”

While the chip is currently used to analyze animal brain cells, this increased resolution and the ability to make long-term recordings is bringing the technology one step closer to being effective in the recording of human brain cell activity.

“Human brain cell signals are smaller and therefore require more sensitive electronic tools to be designed to pick up the signals,” says Colin Dalton, adjunct professor in the Department of Electrical and Computer Engineering at the Schulich School of Engineering and a co-author on this study. Dalton is also the facility manager of the University of Calgary’s Advanced Micro/nanosystems Integration Facility (AMIF), where the chips were designed and fabricated.

Researchers hope the technology will one day be used as a tool to bring personalized therapeutic options to patients facing neurological disease.

Can the brain feel it? The world’s smallest extracellular needle-electrodes

A research team in the Department of Electrical and Electronic Information Engineering and the Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) at Toyohashi University of Technology developed 5-μm-diameter needle-electrodes on 1 mm × 1 mm block modules. This tiny needle may help solve the mysteries of the brain and facilitate the development of a brain-machine interface. The research results were reported in Scientific Reports on Oct 25, 2016.

(Image caption: Extracellular needle-electrode with a diameter of 5 μm mounted on a connector)

The neuron networks in the human brain are extremely complex. Microfabricated silicon needle-electrode devices were expected to be an innovation that would be able to record and analyze the electrical activities of the microscale neuronal circuits in the brain.

However, smaller needle technologies (e.g., needle diameter < 10 μm) are necessary to reduce damage to brain tissue. In addition to the needle geometry, the device substrate should be minimized not only to reduce the total amount of damage to tissue but also to enhance the accessibility of the electrode in the brain. Thus, these electrode technologies will realize new experimental neurophysiological concepts.

A research team in the Department of Electrical and Electronic Information Engineering and the EIIRIS at Toyohashi University of Technology developed 5- μm-diameter needle-electrodes on 1 mm × 1 mm block modules.

The individual microneedles are fabricated on the block modules, which are small enough to use in the narrow spaces present in brain tissue; as demonstrated in the recording using mouse cerebrum cortices. In addition, the block module remarkably improves the design variability in the packaging, offering numerous in vivo recording applications.

“We demonstrated the high design variability in the packaging of our electrode device, and in vivo neuronal recordings were performed by simply placing the device on a mouse’s brain. We were very surprised that high quality signals of a single unit were stably recorded over a long period using the 5-μm-diameter needle,” explained the first author, Assistant Professor Hirohito Sawahata, and co-author, researcher Shota Yamagiwa.

The leader of the research team, Associate Professor Takeshi Kawano said: “Our silicon needle technology offers low invasive neuronal recordings and provides novel methodologies for electrophysiology; therefore, it has the potential to enhance experimental neuroscience.” He added, “We expect the development of applications to solve the mysteries of the brain and the development of brain–machine interfaces.”

Fructose alters hundreds of brain genes, which can lead to a wide range of diseases

A range of diseases — from diabetes to cardiovascular disease, and from Alzheimer’s disease to attention deficit hyperactivity disorder — are linked to changes to genes in the brain. A new study by UCLA life scientists has found that hundreds of those genes can be damaged by fructose, a sugar that’s common in the Western diet, in a way that could lead to those diseases.

However, the researchers discovered good news as well: An omega-3 fatty acid known as docosahexaenoic acid, or DHA, seems to reverse the harmful changes produced by fructose.

“DHA changes not just one or two genes; it seems to push the entire gene pattern back to normal, which is remarkable,” said Xia Yang, a senior author of the study and a UCLA assistant professor of integrative biology and physiology. “And we can see why it has such a powerful effect.”

DHA occurs naturally in the membranes of our brain cells, but not in a large enough quantity to help fight diseases.

“The brain and the body are deficient in the machinery to make DHA; it has to come through our diet,” said Fernando Gomez-Pinilla, a UCLA professor of neurosurgery and of integrative biology and physiology, and co-senior author of the paper.

DHA strengthens synapses in the brain and enhances learning and memory. It is abundant in wild salmon and, to a lesser extent, in other fish and fish oil, as well as walnuts, flaxseed, and fruits and vegetables, said Gomez-Pinilla, who also is a member of UCLA’s Brain Injury Research Center.

Americans get most of their fructose in foods that are sweetened with high-fructose corn syrup, an inexpensive liquid sweetener made from corn starch, and from sweetened drinks, syrups, honey and desserts. The Department of Agriculture estimates that Americans consumed an average of about 27 pounds of high-fructose corn syrup in 2014. Fructose is also found is in most baby food and in fruit, although the fiber in fruit substantially slows the body’s absorption of the sugar — and fruit contains other healthy components that protect the brain and body, Yang said.

To test the effects of fructose and DHA, the researchers trained rats to escape from a maze, and then randomly divided the animals into three groups. For the next six weeks, one group of rats drank water with an amount of fructose that would be roughly equivalent to a person drinking a liter of soda per day. The second group was given fructose water and a diet rich in DHA. The third received water without fructose and no DHA.

After the six weeks, the rats were put through the maze again. The animals that had been given only the fructose navigated the maze about half as fast than the rats that drank only water — indicating that the fructose diet had impaired their memory. The rats that had been given fructose and DHA, however, showed very similar results to those that only drank water — which strongly suggests that the DHA eliminated fructose’s harmful effects.

Other tests on the rats revealed more major differences: The rats receiving a high-fructose diet had much higher blood glucose, triglycerides and insulin levels than the other two groups. Those results are significant because in humans, elevated glucose, triglycerides and insulin are linked to obesity, diabetes and many other diseases.

The research team sequenced more than 20,000 genes in the rats’ brains, and identified more than 700 genes in the hypothalamus (the brain’s major metabolic control center) and more than 200 genes in the hippocampus (which helps regulate learning and memory) that were altered by the fructose. The altered genes they identified, the vast majority of which are comparable to genes in humans, are among those that interact to regulate metabolism, cell communication and inflammation. Among the conditions that can be caused by alterations to those genes are Parkinson’s disease, depression, bipolar disorder, and other brain diseases, said Yang, who also is a member of UCLA’s Institute for Quantitative and Computational Biosciences.

Of the 900 genes they identified, the researchers found that two in particular, called Bgn and Fmod, appear to be among the first genes in the brain that are affected by fructose. Once those genes are altered, they can set off a cascade effect that eventually alters hundreds of others, Yang said.

That could mean that Bgn and Fmod would be potential targets for new drugs to treat diseases that are caused by altered genes in the brain, she added.

The research also uncovered new details about the mechanism fructose uses to disrupt genes. The scientists found that fructose removes or adds a biochemical group to cytosine, one of the four nucleotides that make up DNA. (The others are adenine, thymine and guanine.) This type of modification plays a critical role in turning genes “on” or “off.”

The research is published online in EBioMedicine, a journal published jointly by Cell and The Lancet. It is the first genomics study of all the genes, pathways and gene networks affected by fructose consumption in the regions of the brain that control metabolism and brain function.

Previous research led by Gomez-Pinilla found that fructose damages communication between brain cells and increases toxic molecules in the brain; and that a long-term high-fructose diet diminishes the brain’s ability to learn and remember information.

“Food is like a pharmaceutical compound that affects the brain,” said Gomez-Pinilla. He recommends avoiding sugary soft drinks, cutting down on desserts and generally consuming less sugar and saturated fat.

Although DHA appears to be quite beneficial, Yang said it is not a magic bullet for curing diseases. Additional research will be needed to determine the extent of its ability to reverse damage to human genes.

ofc I'm coming to Tumblr for things like this :p

so basically, I've never been plural in my life and I for sure don't think I am. but I'm talking to something that's like a part of me like in my mind I think? I don't think I'm plural but when I have hour long conversations with myself I feel like there is something there listening and that's why they flow so well in my brain. does anyone have any idea of what this is, am I just weird

Healthy foods do not only help you become fit it can also make you intelligent. You just have to choose the right ones. https://goo.gl/Z14adJ

pensándolo 

Everytime I finish an exam

It’s like:

Zombie para “El Corán y el Termotanque! El Corán y el Termotanque

https://www.facebook.com/ElCoranyelTermotanque?fref=ts

Ilustraciones para la revista “EL CORÁN Y EL TERMOTANQUE” https://www.facebook.com/ElCoranyelTermotanque?fref=ts El Corán y el Termotanque