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Good bacteria may eliminate bad bacteria better than antibiotics

Experimental technology is like a microscopic poison arrow shot from a good bacterium to eliminate a bad bacterium under specific conditions.

The bacteria wars are coming. Researchers at Tel Aviv University have pitted “good” bacteria against “bad” bacteria and the good guys, it appears, are winning.

If the system can be scaled, this new approach could potentially replace antibiotics, which are increasingly struggling against antibiotic-resistant “superbugs.” For the TAU study, the researchers used a toxin injection system known as a “Type 6 Secretion System.” It’s usually deployed by pathogenic (“bad”) bacteria. They introduced the system into a “friendly” bacterium, Vibrio natriegens, which is not harmful to humans. The researchers described their technology as similar to a microscopic poison arrow shot from a good bacterium to eliminate a bad bacterium under specific conditions. “The system that we built allows us to engineer ‘good’ bacteria that can recognize pathogenic bacteria, attack them with toxins, and neutralize them,” explains Dr. Dor Salomon, who co-led the study. “We know how to change and control every component in the system and create a bacterium that neutralizes different strains of bacteria. This is proof of feasibility, showing that we have the knowledge and ability to create bacteria that take advantage of this killing system and may serve as antibiotic treatments. ”The current bacteria prototype is best suited for bugs that occur naturally in saltwater. This is a growing concern, as fish and seafood constitute a major food source in many regions of the world. “Their productivity is severely impaired as a result of bacteria-borne diseases,” Solomon notes, “and since we want to avoid pouring antibiotics into aquaculture farms, a biological solution such as the one we have developed is an effective alternative.” The system will eventually be adapted to treat pathogenic bacteria in humans, farm animals and plants. Tel Aviv University has filed a patent application through Ramot, the university’s technology-transfer company. In addition to Solomon, Dr. Biswanath Jana and Kinga Kappel of the department of clinical microbiology and immunology at TAU’s Sackler Faculty of Medicine participated in the research. The results were published this month in the scientific journal EMBO Reports.

ScienceAlert

Man Bitten by Stray Cat Contracts Infection Unknown to Science

The bite of a fluffy cat on the street can be more dangerous than you might think.

In the United Kingdom, a 48-year-old who was bit by a stray feline ended up contracting a species of bacterium that scientists have never seen before. His immune response to the foreign microorganism was a doozy. Just eight hours after receiving multiple bites, the man's hands had swollen to such a great extent that he took himself to the emergency department. His puncture wounds were cleaned and dressed and he was given a tetanus shot before being sent on his way with antibiotics. A day later, he was back at the hospital. His pinky and middle fingers on his left hand were painfully enlarged and both his forearms were red and swollen. Doctors had to surgically remove the damaged tissue around his wounds. He was also given three different antibiotics intravenously and was sent home with oral antibiotics. This time, thankfully, the treatment worked and he made a full recovery. Back at the hospital, however, doctors were busy trying to figure out what had happened. When they analyzed the microorganisms present in samples from his wounds, they found an unrecognizable Streptococcus-like organism.

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scientists of tumblr, what is a concept that no matter how may times you study it, you'll forget it within 24 hours?