Entanglement Made Simple, A Divulgative Article Of Theoretical Physicist And Nobel Laureate Frank Wilczek,

Check out this 1890s advertisement for cowpox vaccines sold by Lancaster County Vaccine Farms. The advertisement was published as part of the 1893 volume of Polk’s Medical and Surgical Register of the United States.

How viruses infect bacteria: a tale of a tail

To infect bacteria, most bacteriophages employ a ‘tail’ that stabs and pierces the bacterium’s membrane to allow the virus’s genetic material to pass through. The most sophisticated tails consist of a contractile sheath surrounding a tube akin to a stretched coil spring at the nanoscale. When the virus attaches to the bacterial surface, the sheath contracts and drives the tube through it. All this is controlled by a million-atom baseplate structure at the end of the tail. EPFL scientists have now shown, in atomic detail, how the baseplate coordinates the virus’s attachment to a bacterium with the contraction of the tail’s sheath. The breakthrough has made the cover of Nature, and has important implications for science and medicine.

Nicholas M. I. Taylor, Nikolai S. Prokhorov, Ricardo C. Guerrero-Ferreira, Mikhail M. Shneider, Christopher Browning, Kenneth N. Goldie, Henning Stahlberg, Petr G. Leiman. Structure of the T4 baseplate and its function in triggering sheath contraction. Nature, 2016; 533 (7603): 346 DOI: 10.1038/nature17971

Bacteriophages are viruses that infect bacteria. Using state-of-the-art tools, EPFL scientists have described a million-atom “tail” that bacteriophages use to breach bacterial surfaces. The breakthrough has major implications for science and medicine, as bacteriophages are widely used in research.

Mary Anning

Mary Anning was born on 21 May in 1799, one of the most famous fossil finders of her day. This large skull was collected by Anning and is part of the skull and lower jaw of an ichthyosaur (Ichthyosaurus platyodon).

Mary Anning’s family had earned a living for years by gathering fossils on the shore at Lyme Regis in Dorset to sell to collectors. Mary learned about the fossils from her parents, Richard and Mary (‘Molly’) Anning. Despite the lack of a formal education, Mary Anning became an expert on the fossils she found, and the most eminent geologists of the day often sought her advice. In the 1820s she became the first person in Britain to find complete specimens of an ichthyosaur, a plesiosaur and a pterodactyl.

The specimens that Anning collected can still be found in museums throughout Britain. The British Museum purchased this example shortly after Anning discovered it.

On loan from the Natural History Museum.

NASA’s new searchable media library is a treasure trove of space pics and video

Do you like space? Do you like looking at it, wishing you were there instead of here, perhaps? Well NASA just did something that will make your day. The U.S...

The U.S. space agency launched a new web-based search engine for much of its catalog of images, video and audio files, which you can browse by keyword and metadata, so that you never have to remember the dismal reality that you’re earthbound ever again.

A temperature chart for my fellow Americans who can’t do the Celsius-Fahrenheit equation from memory and for people in the civilized countries who’re too busy making fun of Fahrenheit to do the conversions themselves.

Southeast Asia before ASEAN: An ASEAN 50 Commemorative Post

Ironically, the region of Southeast Asia was not an Asian concept. It was a Western one. It was perceived primarily through Western eyes as maps were created during the colonial rush to Asia from the 16th to the early 20th century. Hence, it originated as a geographical concept, having been rendered in different words by Western scholarship, especially before the Second World War– words such as “south east Asia”, “southeast Asia” or “south-east Asia.” In the 1930s for example, Southeast Asia was referred to as “Further India” (as if to allude that it’s near the Bay of Bengal, when it is not) or “Asia of the Monsoons” (to refer to the typhoons that frequently ravage the area.” The regional name’s gradual standardization (no longer in the lowercase “southeast”) and the dropping of the hyphen resulted in the name “Southeast Asia.” It was first used and asserted by the Americans, with its U.S. State Department’s “division of Southeast Asian Affairs” and came to be used frequently by the media as the Second World War sparked in the Pacific in 1941.

After the war, the term “Southeast Asia” transformed from a geographic entity to be referred to, to a complex and inchoate group of nations trying to redefine themselves in the world. As each one dropped their colonial fetters and became independent–Indonesia from the Dutch (17 August 1945), Vietnam from the British (2 September 1945), the Philippines from the United States (4 July 1946), Myanmar from the British (4 January 1948), Laos (22 October 1953) and Cambodia (9 November 1953) from the French, Singapore and Malaysia from the British (16 September 1956), Brunei from the British (1 January 1984), with Thailand successfully retaining its sovereignty, each one has tried to redefine their identities apart from their colonial past. With ideological conflicts in parts of Asia, a Southeast Asian integration seems far off. 

*Front page of the Southeast Asia Collective Defense Treaty, 8 September 1954, from the Archives New Zealand. The first attempt at a Southeast Asian cooperation was done in 1954. The United States initiated an alliance that was meant to contain Communism in Asia, and hence, on 8 September 1954, the Southeast Asia Collective Defense Treaty (or the Manila Pact) was signed by only two Southeast Asian countries–the Philippines and Thailand–and joined by the United States, France, Great Britain, New Zealand, Australia, Thailand, and Pakistan. This established the Southeast Asian Treaty Organization or SEATO, where all member countries agree that if any one of them were attacked, all the other member countries would come to its defense–very similar to the North Atlantic Treaty Organization (NATO). But SEATO would end as a failure, for the simple reason that it was seen suspiciously by the rest of Southeast Asia as “a fig leaf for the nakedness of American policy.” Pakistan withdrew in 1972, and France in 1975.

*Philippine President Macapagal, Indonesian President Sukarno and Malaysian Prime Minister Tunku Abdul Rahman signing agreements forming the MaPhiLindo on 5 August 1963 at the Juan Luna Hall of the Department of Foreign Affairs in Manila, from the Malacañang Presidential Museum and Library.

*The Philippine Commonwealth Government-in-Exile proposed a union with Indonesia in 1943, a Pan-Malayan principle reflected in this part of an American 1942 map entitled “Outline of the Post-War New World Map,” a proposed political boundary map at the event that the Allied forces would win World War II. The one marked in blue are the proposed American protectorates of the post-war world.

At almost the same time, another effort was put in at the time of President Diosdado Macapagal. Coming from our commonality as Malays (with the vision of the late President Manuel L. Quezon for a Pan-Malayan nationhood), President Macapagal envisioned a cooperation with other Malay countries. Hence, Macapagal convened a summit in Manila, together with Malaysian Prime Minister Tunku Abdul Rahman and Indonesian President Sukarno, where they signed the Manila Accord on 5 August 1963, addressing controversial issues over North Borneo and Sarawak joining the Federation of Malaysia. The Accord established the Maphilindo, striving for “Asian solutions by Asian nations for Asian problems.” However, this was also seen as a move by the Philippines and Indonesia to stall or halt the formation of the Federation of Malaysia, which eventually happened on 16 September 1963. Indonesia pulled out of the organization, in reaction to Malaysia’s formation which was seen by Indonesia as a threat to its sovereignty, hence the org’s dissolution.

*The five “Founding Fathers” of the ASEAN, signing the Bangkok Declaration, also known as the ASEAN Declaration, on 8 August 1967. From the ASEAN Archive.

This explains the tensed environment that the five Foreign Ministers of Southeast Asia found themselves in on 8 August 1967 in the Thai Department of Foreign Affairs in Bangkok, Thailand. Carefully, and diplomatically, these representatives from Indonesia (Adam Malik), Malaysia (Tun Abdul Razak), Singapore (S. Rajaratnam), Philippines (Narciso Ramos) and Thailand (Thanat Khoman), sat down together, chose their words carefully, patiently wrestled on their issues through dialogue, and bravely met on common ground. It entailed a larger vision, one that did not only concern each of their nation’s concerns, but one that gave space to regional unity in spite of their differences. Rajaratnam said to his counterparts on that day:

We must think not only of our national interests but posit them against regional interests: that is a new way of thinking about our problems. And these are two different things and sometimes they can conflict. Secondly, we must also accept the fact, if we are really serious about it, that regional existence means painful adjustments to those practices and thinking in our respective countries. We must make these painful and difficult adjustments. If we are not going to do that, then regionalism remains a utopia.

“Painful adjustments” indeed. After all was said and done, the five Foreign Ministers, representing their heads of state, after months of negotiations and compromise, finally and unequivocally signed the two-page ASEAN Declaration, establishing the Association of Southeast Asian Nations, and committing themselves to resolving disputes by peaceful means and through hard but committed mutual accommodation. Bereft of the colonial baggages of the previous southeast asian intergovernmental organizations, it was Southeast Asian, from the inception of the idea to its founding. 

The founding of the ASEAN in 1967 led to the diplomatic reconciliation between Malaysia and Indonesia, and Malaysia and Singapore. And while a year later, Malaysia temporarily severed its diplomatic relations with the Philippines due to claims over Sabah, this kind of issues never impeded the commitment the two nations have in ASEAN, so was with the other member-states with similar problems. Since then, ASEAN has grown into a 10-member-state organization. This probably explains why ASEAN is “the most successful inter-governmental organization in the developing world today.”

In the occasion of the Philippine Chairmanship of the ASEAN and its 50th founding anniversary, Happy ASEAN 50th!

*Banner from ASEAN 50 Facebook. 

*Post-script: The deafening silence of the Philippines with its unprecedented win in the arbitration ruling in the ASEAN meetings ought to make people question our foreign policy. Insisting on our sovereign rights over our EEZ does not mean war-mongering. Vietnam, on the other hand, the nation that defeated the United States in the Vietnam War, still insists the rule of law thus challenging Chinese encroachment diplomatically. It exemplifies a fair and “independent foreign policy.” The Philippines should follow Vietnam’s example. 

*Map above: “South-east Asia” map made by Polish Army Topography Service as featured in Pergamon World Atlas in 1967, the year ASEAN was founded. From the David Rumsey Historical Map Collection. 

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The Icelandic Language still uses the letters Þ and Ð, which used to be in the English alphabet too but which fell into disuse and were eventually left out altogether. Their pronunciation is the sound made by the “th” in “this” and “that” respectively.

Incidentally, the Þ was not included in early English printing press types. As a substitute they used y, which looks somewhat similar. Thus was the popular misconception born that English people used to say “ye” as in “ye old shoppe.”

Are humans the new supercomputer?

The saying of philosopher René Descartes of what makes humans unique is beginning to sound hollow. ‘I think – therefore soon I am obsolete’ seems more appropriate. When a computer routinely beats us at chess and we can barely navigate without the help of a GPS, have we outlived our place in the world? Not quite. Welcome to the front line of research in cognitive skills, quantum computers and gaming.

Today there is an on-going battle between man and machine. While genuine machine consciousness is still years into the future, we are beginning to see computers make choices that previously demanded a human’s input. Recently, the world held its breath as Google’s algorithm AlphaGo beat a professional player in the game Go—an achievement demonstrating the explosive speed of development in machine capabilities.

But we are not beaten yet - human skills are still superior in some areas. This is one of the conclusions of a recent study by Danish physicist Jacob Sherson, published in the prestigious science journal Nature.

”It may sound dramatic, but we are currently in a race with technology—and steadily being overtaken in many areas. Features that used to be uniquely human are fully captured by contemporary algorithms. Our results are here to demonstrate that there is still a difference between the abilities of a man and a machine,” explains Jacob Sherson.

At the interface between quantum physics and computer games, Sherson and his research group at Aarhus University have identified one of the abilities that still makes us unique compared to a computer’s enormous processing power: our skill in approaching problems heuristically and solving them intuitively. The discovery was made at the AU Ideas Centre CODER, where an interdisciplinary team of researchers work to transfer some human traits to the way computer algorithms work. 


Quantum physics holds the promise of immense technological advances in areas ranging from computing to high-precision measurements. However, the problems that need to be solved to get there are so complex that even the most powerful supercomputers struggle with them. This is where the core idea behind CODER—combining the processing power of computers with human ingenuity—becomes clear. 


Our common intuition Like Columbus in QuantumLand, the CODER research group mapped out how the human brain is able to make decisions based on intuition and accumulated experience. This is done using the online game “Quantum Moves”. Over 10,000 people have played the game that allows everyone contribute to basic research in quantum physics.

"The map we created gives us insight into the strategies formed by the human brain. We behave intuitively when we need to solve an unknown problem, whereas for a computer this is incomprehensible. A computer churns through enormous amounts of information, but we can choose not to do this by basing our decision on experience or intuition. It is these intuitive insights that we discovered by analysing the Quantum Moves player solutions,” explains Jacob Sherson. 


The laws of quantum physics dictate an upper speed limit for data manipulation, which in turn sets the ultimate limit to the processing power of quantum computers—the Quantum Speed ​​Limit. Until now a computer algorithm has been used to identify this limit. It turns out that with human input researchers can find much better solutions than the algorithm.

"The players solve a very complex problem by creating simple strategies. Where a computer goes through all available options, players automatically search for a solution that intuitively feels right. Through our analysis we found that there are common features in the players’ solutions, providing a glimpse into the shared intuition of humanity. If we can teach computers to recognise these good solutions, calculations will be much faster. In a sense we are downloading our common intuition to the computer” says Jacob Sherson.

And it works. The group has shown that we can break the Quantum Speed Limit by combining the cerebral cortex and computer chips. This is the new powerful tool in the development of quantum computers and other quantum technologies.

We are the new supercomputer

Science is often perceived as something distant and exclusive, conducted behind closed doors. To enter you have to go through years of education, and preferably have a doctorate or two. Now a completely different reality is materialising. 


In recent years, a new phenomenon has appeared—citizen science breaks down the walls of the laboratory and invites in everyone who wants to contribute. The team at Aarhus University uses games to engage people in voluntary science research. Every week people around the world spend 3 billion hours playing games. Games are entering almost all areas of our daily life and have the potential to become an invaluable resource for science.

“Who needs a supercomputer if we can access even a small fraction of this computing power? By turning science into games, anyone can do research in quantum physics. We have shown that games break down the barriers between quantum physicists and people of all backgrounds, providing phenomenal insights into state-of-the-art research. Our project combines the best of both worlds and helps challenge established paradigms in computational research,” explains Jacob Sherson.

The difference between the machine and us, figuratively speaking, is that we intuitively reach for the needle in a haystack without knowing exactly where it is. We ‘guess’ based on experience and thereby skip a whole series of bad options. For Quantum Moves, intuitive human actions have been shown to be compatible with the best computer solutions. In the future it will be exciting to explore many other problems with the aid of human intuition.

"We are at the borderline of what we as humans can understand when faced with the problems of quantum physics. With the problem underlying Quantum Moves we give the computer every chance to beat us. Yet, over and over again we see that players are more efficient than machines at solving the problem. While Hollywood blockbusters on artificial intelligence are starting to seem increasingly realistic, our results demonstrate that the comparison between man and machine still sometimes favours us. We are very far from computers with human-type cognition,” says Jacob Sherson and continues:

“Our work is first and foremost a big step towards the understanding of quantum physical challenges. We do not know if this can be transferred to other challenging problems, but it is definitely something that we will work hard to resolve in the coming years.”

Your pocket Constitution

The amazing Khizr Khan was onto something with his pocket U.S. Constitution - and our Labs team went ahead and made an app for that. Understanding the U.S. Constitution is an app that allows you to view the articles and amendments of the Constitution, and then links you to scholarship relating to each specific section. It’s free for iOS and Android. Keep fighting the good fight against “alternative facts.” 

More here: http://labs.jstor.org/constitution/

初代「ゴジラ」俳優、中島春雄さん死去 http://www.bbc.com/japanese/40860452